CannaCured Canada has long recognized the unique properties of cannabis, a plant known by various names. A key characteristic of cannabis plants is the presence of numerous substances called cannabinoids or phytocannabinoids.
Research in biomechanics and the therapeutic effects of these compounds is leading to the creation of various applications for these plants, offering hope to those in search of relief from their symptoms.
Let us explore the components of the cannabis plant and consider how to access cannabis if you wish to experience its potential benefits.
Table of Contents
Key Takeaways:
- The cannabis plant consists of substances such as cannabinoids, terpenes, and flavonoids.
- The harmonious interaction of compounds in cannabis creates a phenomenon known as the entourage effect.
- Full-spectrum cannabis extracts tend to offer greater medical benefits compared to isolated components of the plant.
The Cannabis Plants and Its Major Components
Cannabis, part of the Cannabaceae family, which includes hops, is marked by secondary substances known as cannabinoids or phytocannabinoids. More than 150 cannabinoids exist alongside terpenoids, flavonoids, and alkaloids.
Cannabinoids
Cannabinoids are naturally occurring compounds primarily found in the flower buds of the cannabis plant. Known as phytocannabinoids due to their botanical origin, they are crucial to the plant’s makeup. Notably, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most recognized and studied.
Terpenes
Terpenes are aromatic compounds that significantly influence the flavor and aroma of cannabis. They are not exclusive to cannabis but are found across various plant species.
Over 140 terpenes have been identified in cannabis alone, each contributing distinct characteristics. Among these, B-myrcene is the most prevalent, followed by trans-caryophyllene and a-pinene.
Flavonoids
Flavonoids are natural compounds found in many plants, contributing to their vibrant colors. In cannabis, they work alongside terpenes and cannabinoids, displaying anti-inflammatory and neuroprotective properties. Certain flavonoids, like apigenin, show anxiolytic and estrogenic effects, while cannaflavins A and B are recognized for their strong anti-inflammatory abilities.
Molecules Journal: Exploring the Combined Components of Cannabis and Its Impact on Therapeutic Benefits
An analysis by NORML indicates that over 32,000 marijuana studies have been published in the last decade. While much of this research focuses on the effects of cannabis consumption, other components like cannabinoids, terpenes, and flavonoids have been somewhat overlooked, with the majority centering on THC and CBD.
The journal Molecules examines the interactions among various chemical compounds in marijuana, emphasizing the importance of understanding how these elements collaborate to unveil cannabis’s therapeutic potential.
Understanding the Significance of the Endocannabinoid System
The endocannabinoid system (ECS) plays a vital role in regulating numerous physiological processes within the nervous system. Dysregulation of the ECS is linked to several medical conditions, and therapeutic approaches targeting ECS activity have shown promise in managing neuroinflammation-related issues. The ECS comprises a complex network of receptors, endocannabinoids derived from arachidonic acid, receptor ligands, and enzymes that facilitate endocannabinoid metabolism.
The ECS, featuring endocannabinoids like anandamide and 2-arachidonoylglycerol, alongside the enzymes that produce and break them down, as well as the cannabinoid receptors CB1 and CB2, is one of the most widespread signaling systems in the brain. It influences functions such as stress response, anxiety, memory, pain perception, and motivated behavior, playing a key role in the development and refinement of neural circuits during adolescence.
The Entourage Effect of Cannabis Components within the ECS
The entourage effect illustrates how the interaction of co-existing metabolites can alter the properties of individual molecules, even if those metabolites lack inherent pharmacological activity.
Preclinical studies in Molecules Journal (2019) and Oncotarget Journal (2020) highlight the interplay between phytocannabinoids and terpenes, suggesting that the therapeutic benefits of full-spectrum cannabis extracts may arise from what is known as the entourage effect.
Cannabinoids
Research published in the British Journal of Pharmacology and Multiple Sclerosis and Related Disorders observed the combined effect of THC and CBD on neuroinflammation in animal models of multiple sclerosis. Phytocannabinoids demonstrate immunomodulatory and anti-inflammatory properties. For example, THC and CBD exhibit differing mechanisms when tested on LPS-activated microglial cells.
Terpenes
In the Journal of Pharmacology, Cheng et al. (2014) found that β-caryophyllene, a terpene, binds to CB2R receptors, potentially aiding the combined effects of phytochemicals in C. sativa to alleviate neurotoxicity associated with Alzheimer’s disease.
Myrcene’s ability to enhance delta-9-THC transport across the blood-brain barrier presents a fascinating opportunity for developing Alzheimer’s therapeutics that effectively reach the central nervous system.
Flavonoids
Flavonoids may help combat oxidative stress and neurodegeneration, enhancing the neuroprotective properties associated with the entourage effect. A review in Frontiers in Aging Neuroscience highlighted the neuroprotective advantages of various flavonoids, showing their potential to reduce neuroinflammation and neurodegenerative processes.
The Authors Take
Understanding the complex interactions between cannabinoids, terpenes, and flavonoids is crucial for unlocking the full therapeutic benefits of cannabis, as noted by the authors of the study. They also identify significant gaps in evidence that need urgent attention.
- Researching the synergistic effects and mechanisms of cannabinoids, terpenes, and flavonoids requires focused effort.
- Understanding cannabis phytochemical production and accumulation mechanisms, particularly under different lighting conditions, is key to advancing medicinal applications.
- A thorough phytochemical characterization of cannabis strains, including their specific ratios of cannabinoids, terpenes, and flavonoids, can enhance treatment approaches, leading to more personalized and effective medicinal solutions.
Where to Buy Weed?
If you are curious about the potential health benefits of cannabis but are uncertain where to begin, mail-order marijuana services and same-day cannabis delivery provide convenient options to access cannabis products. These platforms feature a user-friendly website that allows you to explore various products from the comfort of your home.
Purchasing cannabis online not only gives you access to affordable options and promotional discounts but also allows you to discover high-quality cannabis products suited to your preferences.
Conclusion
Cannabis contains a variety of compounds, each capable of producing unique effects. The synergy among these compounds enhances their therapeutic potential beyond initial expectations. Research, including studies published in the Molecules journal, offers valuable insights into cannabis mechanisms, emphasizing the importance of full-spectrum products for symptom management. Although more targeted studies are needed, initial findings provide encouraging glimpses into the possibilities and understanding.
Frequently Asked Questions
How much does it cost to buy cannabis online in Canada?
The price of cannabis per gram is relatively affordable in Canada compared to the US. In physical dispensaries, a gram ranges from $10 to $12, while online dispensaries often offer options starting at $2 per gram. A gram of cannabis online may cost around $5 for satisfactory quality, typically in the AA+ to AAA grade range.
Can medical and recreational marijuana differ in price?
Cannabis can be consumed for medical or recreational purposes, with medical cannabis generally being less expensive than recreational varieties. Medical cannabis costs may be eligible for tax deductions, and insurance coverage may sometimes help offset expenses.
Are other marijuana products as affordable as cannabis flower?
Buying cannabis online is generally more economical than traditional sources. Alternative products like edibles, capsules, and oils may be priced slightly higher, but they remain reasonably priced. Online dispensaries strive to maintain competitive rates within the cannabis market.
Is bulk cannabis cheaper than per gram?
Yes, purchasing cannabis in bulk often results in discounts compared to buying per gram. This is particularly advantageous for regular users or those needing medical cannabis. Buying per gram is ideal for initial experimentation.
Does cheap cannabis mean low quality?
While price can indicate cannabis quality, it is not the only factor to consider. Many assume that inexpensive cannabis is of inferior quality, but that is not always the case. It can sometimes signify a batch nearing its expiration date, leading dispensaries to sell it at a lower price for timely turnover. Evaluating cannabis solely based on price may overlook aspects that contribute to its overall value and experience.
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