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Unstable Personality Disorder | CannaCured Canada

Emotionally Unstable Personality Disorder (EUPD), commonly referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional stability, and may result in impulsive or self-harming actions. Treatment can be expensive, with success rates fluctuating between 35% and 50%. Researchers are investigating alternative therapies to support traditional treatment methods.

A potential addition to EUPD treatment is cannabis, also known as weed. Its affordability and beneficial components can aid patients with EUPD. Individuals unable to afford multiple treatments might consider CannaCured Canada for cannabis deals that provide cost-effective solutions.

Key Takeaways:

  • Participants with EUPD who inhaled THC or used high CBD reported positive outcomes in symptom management.
  • High doses of CBD (800 mg/day) alongside THC flower treatment can elevate circulating levels of anandamide.
  • Dysfunction in the endocannabinoid system, which governs emotions and stress, plays a role in Emotionally Unstable Personality Disorder.

Emotionally Unstable Personality Disorder or Borderline Personality Disorder

EUPD is a mental health condition affecting self-perception and interpersonal relationships, often leading to challenges in daily life. It is characterized by intense, unstable relationships, impulsiveness, and a distorted self-image.

While the exact causes remain uncertain, factors such as genetics, trauma, and neurotransmitter imbalances may contribute. Dysfunction within the endocannabinoid system, which regulates emotional responses and stress, may exacerbate EUPD symptoms.

EUPD Treatment

Despite guidelines indicating that no medications are proven effective for EUPD, clinicians frequently prescribe treatments such as antipsychotics and antidepressants.

Antipsychotic and sedative medications can be beneficial for short-term crisis management or addressing comorbid conditions. Reports suggest that up to 90% of EUPD patients take at least one psychotropic medication, including antipsychotics, antidepressants, mood stabilizers, and sedatives.

Polypharmacy is prevalent among these individuals. Many of these medications come with side effects and are often used off-label for EUPD. Although certain drugs may alleviate specific symptoms, they do not alter the overall prognosis of the disorder.

Cannabis-Based Medicine for EUPD (CBM)

Cannabis-based medicines are derived from the cannabis plant, containing cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD). These products are utilized to address medical issues and symptoms, including pain, inflammation, anxiety, and seizures.

Numerous studies have explored the mental health effects of cannabis. Research published in Frontiers in Psychiatry indicates that marijuana may enhance mood and improve sleep quality and overall life satisfaction. These insights warrant further investigation into cannabis’s impact on various mental health disorders.

CBM for Unstable Personality Disorder

A narrative review and case series conducted in 2022 examined cannabinoids for EUPD symptom management in seven patients. The researchers assessed cellular and molecular mechanisms, reviewing current evidence for cannabis-based medicinal products (CBMP) as a potential EUPD treatment.

Materials and Methods

Participants were diagnosed with EUPD and had previously attempted at least one medication and one form of psychotherapy, with at least one follow-up review at a Zerenia clinic, including patient-reported outcome measures (PROMS).

CBM used included dried flower for inhalation (20-60g per month) and oral extracts with THC (9-10mg/day) and CBD (40mg/day). Formulations were categorized by chemotype: Chemotype 1 (High THC, low CBD), Chemotype 2 (Balanced THC and CBD), Chemotype 3 (High CBD, low THC).

Measurements were taken using the Clinical Global Impression Improvement (CGI-I) Scale and the Patient’s Global Impression of Change (PGIC) Scale.

Researchers tailored dosing through gradual increases and provided guidelines for dose adjustments until satisfactory symptom management or side effects were observed.

Results

At one-month follow-up, six participants noted improvements, with five rating their progress as a six on the PGIC scale. Only one individual, treated with a chemotype 2 oral extract, reported no benefits, suggesting that inhaled THC or higher oral CBD doses might be more effective.

All participants tolerated the treatment well, with no side effects reported, which is crucial for adherence. Younger patients might feel more at ease with medical cannabis, despite societal stigma.

Hypothesis

Researchers propose that exogenous cannabinoids may help restore the tonic activation of the endocannabinoid system (ECS) within the central nervous system (CNS). THC directly activates presynaptic CB1 receptors, with both cannabinoids binding to fatty-acid binding proteins (FABPs), potentially slowing anandamide deactivation.

High doses of oral CBD (800 mg/day) and patients treated with chemotype 1 flower exhibit elevated anandamide levels. It remains uncertain whether this is due to CBD affecting anandamide transport or degradation or other molecular target interactions. In contrast, psychiatric drugs commonly take 2-3 weeks to show initial effects, with longer durations for full remission.

Rapid symptom relief can be crucial during an “EUPD crisis,” when distressed individuals may resort to benzodiazepines and other anxiety medications, which can lead to tolerance and dependence.

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Manage Changes in Behaviour with Bulk cannabis Via Mail-Order Marijuana Service

Cannabinoids effectively manage unstable personality disorders by targeting the ECS to maintain anandamide balance. Patients with EUPD can gain from purchasing cannabis online or affordable products to help alleviate their symptoms.

An online cannabis store featuring same-day delivery or mail-order options balances quality and affordability. Experience exceptional customer service from a friendly team and discover a wide array of bulk cannabis strains, edibles, concentrates, and oils to enhance your experience. Buy cannabis online at CannaCured Canada for cannabis.

Frequently Asked Questions

Does cheap marijuana have poor quality?

No, price does not solely determine product quality. You can evaluate quality by examining the product’s physical attributes and testing it yourself. Some dispensaries reduce prices through monthly or clearance sales. If a dispensary’s prices fall below cannabis industry standards, concerns about quality may arise.

Does marijuana cause any adverse effects when managing BPD?

Participants in the study reported no adverse side effects from marijuana use. This is crucial for medication adherence, as a review of 36 studies revealed side effects accounted for 28% of patients’ non-adherence to antipsychotics. A negative perception of antipsychotic medication was the second most common reason for intentional non-adherence, at 30.5%.

What is the quickest way to experience the effects of cannabinoids for an EUPD problem?

Smoking, vaping, and dabbing are the fastest methods to experience cannabinoid effects. In the study, participants used vaping to consume dried flower. Although smoking and vaping have similar effects, the primary difference lies in inhaling smoke (from smoking) versus vapor (from vaping). Dabbing, which involves consuming concentrates, also provides rapid effects.

How many times can I smoke or vape to manage my symptoms?

The effectiveness of cannabis strains and products varies based on individual needs. In the study, researchers permitted patients to adjust their daily dosage (between 0.5 and 2 grams per day) as long as they stayed within the monthly limit. For extracts, patients documented their daily dosages.

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